[4eyes] FW: [Faculty] Seminar: April 23, 2009: Dianna Han
Matthew Turk
mturk at cs.ucsb.edu
Wed Apr 22 11:26:36 PDT 2009
Please attend this talk if you are able. Dianna is now a Four Eyes Lab
student, albeit spending most of her time in our "satellite UCLA lab."
Matthew
-----Original Message-----
From: faculty-bounces at lists.cs.ucsb.edu
[mailto:faculty-bounces at lists.cs.ucsb.edu] On Behalf Of Tiffany Sabado
Sent: Wednesday, April 22, 2009 11:15 AM
To: Typical faculty; grads at lists.cs.ucsb.edu; research at lists.cs.ucsb.edu;
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Subject: [Faculty] Seminar: April 23, 2009: Dianna Han
Thursday, April 23, 2009
CS Conference Room
2 PM
Title: Cognitive State Detection using Functional MRI
Speaker: Dianna Han, PhD student, Computer Science, UCSB
Abstract:
This talk will give an overview of cognitive state detection using fMRI.
Magnetic Resonance Imaging (MRI) is a medical imaging technique based on
the physics of nuclear magnetic resonance. It has been widely used in
radiology to visualize the internal structure and function of the body.
Functional MRI (fMRI) is an indirect measure of neural activity changes
in the brain that uses the MRI equipment to detect changes in cerebral
metabolism. The most popular technique employed in neuroscience studies
utilizes blood oxygenation level dependent (BOLD) contrast. Although the
precise nature of the coupling between neural activity and the BOLD
signal is still an ongoing research subject, it has been observed that
increased neural activity causes an increased amount of oxygenated
hemoglobin relative to deoxygenated hemoglobin in the active region,
which leads to a signal increase detectable by the scanner.
It has been proven that fMRI can be used to detect and characterize
changes in cognitive state. Given the high dimensionality of the data
dimension reduction is an essential step in fMRI data analysis. Common
approaches include creating statistical summaries of individual voxels
using t-test and correlation test, isolating 'regions of interests'
(ROIs), and applying classic dimension reduction methods such as
principle component analysis (PCA). A more attractive approach uses
independent component analysis (ICA), which separates the multivariate
signal into components most effective in classifying the sources by
maximizing the statistical independence among them. Classification
techniques then can be applied to the reduced search space to
discriminate different states.
Functional MRI and its applications of detecting cognitive states have
drawn much research interest. In March 2009 a lie-detection test based
on fMRI was submitted in court as evidence in San Diego. Other
applications such as craving state detection for drug rehabilitation and
diagnosis of mental diseases are also being explored. Efforts have also
been made to improve its temporal resolution (only on the order of
seconds) by combining fMRI with other techniques of higher temporal
resolution such as EEG.
Dianna Han is a Ph.D student in the Department of Computer Science,
UCSB. Her research interest lies in medical image analysis, more
specifically, cognitive state detection using functional MRI and EEG.
Her research advisor is Professor Matthew Turk. She is currently working
on a collaborative research project led by Professor Mark Cohen in UCLA
Center for Cognitive Neuroscience.
Host: Matthew Turk
--
Tiffany Sabado
Assistant to the Chair
Computer Science Department
Phone (805) 893-2207
Fax (805) 893-8553
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